Synthesis and secretion of phospholipase C by oral spirochetes.

نویسندگان

  • R Siboo
  • W al-Joburi
  • M Gornitsky
  • E C Chan
چکیده

Four strains of oral treponemes and Treponema phagedenis Reiter synthesize and secrete phospholipase C (PLC), which was detected by the hydrolysis of p-nitrophenylphosphorylcholine. PLC was detected in gingival crevicular fluid from diseased but not from healthy sulci. The initiation and progression of periodontal lesions may begin with the hydrolysis of membrane phospholipids by PLC.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 27 3  شماره 

صفحات  -

تاریخ انتشار 1989